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Based on the measurement principle, how to choose a suitable particle size analyzer?(一)

2024-05-23
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Based on the measurement principle, how to choose a suitable particle size analyzer?
1. What is light scattering?
When light passes through a non-uniform environment, the phenomenon that part of the light changes its direction of propagation is called light scattering, and this part of the light that changes the direction of propagation is called scattered light. The essence of light scattering phenomenon is the interaction between light and matter.



2. Interaction between particles and light
Microscopically, when a beam of light shines on particles, part of the light is scattered, and part of the light is reflected, refracted, and absorbed. For a few special substances, fluorescence, phosphorescence, etc. may also be produced. When the incident light is coherent monochromatic light, these scattered lights form a specific diffraction pattern after coherence. Mie scattering theory is the scientific expression of this phenomenon. If the particles are spherical, a diffraction pattern called an Airy disk is observed in a plane perpendicular to the incident light.


3. Principle of laser particle size analyzer-spatial distribution detection analysis of light scattering
The instrument that measures and analyzes the dispersed particle size of sample particles by measuring the spatial angle light energy distribution is the static light scattering laser particle size analyzer. Due to the advantages of wide test range, simple test, and good data reproducibility, this method is the most widely used instrument and is usually used. Referred to as laser particle size analyzer.

Laser particle size analyzers are generally best suited for the analysis of sub-micron to millimeter-sized particles.



4. Principle of Nanoparticle Size Analyzer - Time Domain Fluctuation Detection of Light Scattering Analysis
For the measurement of suspended nanoparticles smaller than the laser wavelength, it is generally characterized by measuring the non-directional Brownian motion rate of the nanoparticles in a certain area. Dynamic light scattering technology is used to evaluate the Brownian motion rate at this time, that is, through scattered light It can be calculated by measuring the speed of fluctuation.

Dynamic light scattering nanoparticle size analyzers are suitable for testing particles ranging from a few tenths of a nanometer to several microns.



5. Principle of Zeta Potentiometer - Phase Detection Analysis of Particle Light Scattering in Electrophoresis
Most nanoparticles have relatively active electrochemical properties, and the potential brought by the sliding plane of the nanoparticles in the medium is called the Zeta potential.

Since large particles are more charged, the electrophoretic light scattering method is suitable for measuring the Zeta potential of particles in the range of 2nm-100um and analyzing the potential distribution of particles.


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