Vaccine Bioreactor

Vaccine Bioreactor(GMP) bacteria stirred fermentation tank

Cialan is the first tier manufacturer and supplier of vaccine bioreactor in China, we provide microorganism bioreactor, bacteria bioreactor, stirred fermentation tank and professional after-service.

5L-10KL etc

Volume

Stainless steel

Materials

30%~70%

Working volume

Product Details Parameter Message

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Product Details

Vaccine Bioreactor is a pilot industry size vaccine bioreactor. Efficient, safe and large-scale production of vaccine components such as viruses, virus-like particles (VLPs), recombinant proteins or nucleic acids (mRNA) by optimizing the culture conditions of cells or microorganisms

It meet GMP standards, and ability to offer relative verification documents.

All liquid contact part is SS316L. Accept customize and design.

CN-SCV type is top magnetic drive. CN-SJV is top mechanical drive. CN-SJBV is bottom mechanical drive.

Parameter

Total volume	5L,10L,15L,20L,30L,50L,100L,200L,500L,1000L, 2KL,5KL,10KL etc.
Working volume	30%~70%
Polishing	Electrolytic polishing, precision: 0.2-0.4um.
Stirring system	Mechanical drive or Magnetic drive, 3 height adjustable six – blade stirrer Stir speed: 50~1000rpm/50-350rpm
Sterilization	On-site sterilization(SIP) by auto control
Clean	Clean in place (CIP) by spray ball
Aeration flow	Multi-way ventilation. Auto control by mass flow meter, 1vvm
Feeding	Automatically feeding by fixed peristaltic pump (standard) Variable speed peristaltic pump(optional)
Anti-foam control	Automatically add antifoam by peristaltic pump
Temperature control	Auto-control, electric heating range: water source add 5℃ to 70℃
PH control	2.00-12.00±0.05pH, auto-control by adding acid and base, pH sensor (Hamilton/Mettler, Switzerland)
DO control	0-150±3% displaying precision 0.1%, DO sensor from Hamilton/Mettler, Switzerland. DO coupling with agitation, oxygen.
Sampling valve	Can sterilization separately, manual
Harvest	Zero dead zone bottom valve, can sterilization separately, manual
Weight system	Mettler-Toledo, Switzerland
Pressure	Auto control, BD Germany pressure transmitter or Lambert differential pressure liquid level gauge.
Exhaust	Have condenser before exhaust, control by diagram valve / Proportional control valve.
Control parameters	10in touch screen, Siemens PLC control system with control parameters (stirring, pH, DO, temperature, feeding, gas etc.), data analysis, data logging, data output and printing, overrun alarm, language switching and other functions
Optional configuration	O2/N2/CO2 gas control, Level sensor, OD sensor, Turbidity sensor, ORP sensor, Weight system, Live cell sensor etc.

Fermenter bioreactor build and design cases

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